| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPC_2443 | RPC_2639 | RPC_2443 | RPC_2639 | RseP peptidase. Metallo peptidase. MEROPS family M50B. | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | 0.776 |
| RPC_2443 | RPC_4784 | RPC_2443 | RPC_4784 | RseP peptidase. Metallo peptidase. MEROPS family M50B. | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | 0.651 |
| RPC_2639 | RPC_2443 | RPC_2639 | RPC_2443 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | RseP peptidase. Metallo peptidase. MEROPS family M50B. | 0.776 |
| RPC_2639 | RPC_2642 | RPC_2639 | RPC_2642 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | Conserved hypothetical protein. | 0.831 |
| RPC_2639 | RPC_4784 | RPC_2639 | RPC_4784 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | 0.910 |
| RPC_2639 | era | RPC_2639 | RPC_2641 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.914 |
| RPC_2639 | lepA | RPC_2639 | RPC_0591 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.756 |
| RPC_2639 | parC | RPC_2639 | RPC_2644 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.764 |
| RPC_2639 | recO | RPC_2639 | RPC_2643 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.799 |
| RPC_2639 | rnc | RPC_2639 | RPC_2640 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.956 |
| RPC_2639 | rnhB | RPC_2639 | RPC_4361 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.752 |
| RPC_2639 | secD | RPC_2639 | RPC_2776 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.721 |
| RPC_2642 | RPC_2639 | RPC_2642 | RPC_2639 | Conserved hypothetical protein. | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | 0.831 |
| RPC_2642 | era | RPC_2642 | RPC_2641 | Conserved hypothetical protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.831 |
| RPC_2642 | parC | RPC_2642 | RPC_2644 | Conserved hypothetical protein. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.573 |
| RPC_2642 | recO | RPC_2642 | RPC_2643 | Conserved hypothetical protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.654 |
| RPC_2642 | rnc | RPC_2642 | RPC_2640 | Conserved hypothetical protein. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.831 |
| RPC_4784 | RPC_2443 | RPC_4784 | RPC_2443 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | RseP peptidase. Metallo peptidase. MEROPS family M50B. | 0.651 |
| RPC_4784 | RPC_2639 | RPC_4784 | RPC_2639 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | 0.910 |
| RPC_4784 | lepA | RPC_4784 | RPC_0591 | Signal peptidase I. Serine peptidase. MEROPS family S26A; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.756 |