Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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RPC_4555(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (785 aa)    
Predicted Functional Partners:
RPC_3758
Hydrogenase expression/formation protein HypE.
 
 
 0.974
RPC_4556
Hydrogenase expression/formation protein HypE.
 
 
 0.974
RPC_3760
Hydrogenase assembly chaperone hypC/hupF.
 
 
 0.895
RPC_3759
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.887
RPC_4557
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.887
RPC_4558
Hydrogenase assembly chaperone hypC/hupF.
 
 
 0.861
RPC_4559
Hydrogenase accessory protein HypB.
 
   
 0.817
RPC_4493
Hydrogenase accessory protein HypB.
 
   
 0.816
RPC_3761
Hydrogenase accessory protein HypB.
 
   
 0.811
RPC_4554
Molybdopterin adenylyltransferase.
     
 0.802
Your Current Organism:
Rhodopseudomonas palustris BisB18
NCBI taxonomy Id: 316056
Other names: R. palustris BisB18, Rhodopseudomonas palustris str. BisB18, Rhodopseudomonas palustris strain BisB18
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