node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPC_0769 | RPC_2106 | RPC_0769 | RPC_2106 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid A biosynthesis acyltransferase. | 0.801 |
RPC_0769 | RPC_2447 | RPC_0769 | RPC_2447 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.874 |
RPC_0769 | RPC_4705 | RPC_0769 | RPC_4705 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase-like; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.880 |
RPC_0769 | kdsA | RPC_0769 | RPC_2477 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.989 |
RPC_0769 | kdsB | RPC_0769 | RPC_3731 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.882 |
RPC_0769 | lpxB | RPC_0769 | RPC_2449 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.877 |
RPC_0769 | lpxC | RPC_0769 | RPC_3297 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.875 |
RPC_0769 | lpxD1 | RPC_0769 | RPC_2445 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.868 |
RPC_0769 | lpxD2 | RPC_0769 | RPC_2464 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.867 |
RPC_0769 | lpxK | RPC_0769 | RPC_4704 | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.879 |
RPC_2106 | RPC_0769 | RPC_2106 | RPC_0769 | Lipid A biosynthesis acyltransferase. | KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.801 |
RPC_2106 | RPC_2447 | RPC_2106 | RPC_2447 | Lipid A biosynthesis acyltransferase. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.771 |
RPC_2106 | RPC_4705 | RPC_2106 | RPC_4705 | Lipid A biosynthesis acyltransferase. | Three-deoxy-D-manno-octulosonic-acid transferase-like; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.981 |
RPC_2106 | kdsA | RPC_2106 | RPC_2477 | Lipid A biosynthesis acyltransferase. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.773 |
RPC_2106 | kdsB | RPC_2106 | RPC_3731 | Lipid A biosynthesis acyltransferase. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.808 |
RPC_2106 | lpxB | RPC_2106 | RPC_2449 | Lipid A biosynthesis acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.801 |
RPC_2106 | lpxC | RPC_2106 | RPC_3297 | Lipid A biosynthesis acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.761 |
RPC_2106 | lpxD1 | RPC_2106 | RPC_2445 | Lipid A biosynthesis acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.746 |
RPC_2106 | lpxD2 | RPC_2106 | RPC_2464 | Lipid A biosynthesis acyltransferase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.727 |
RPC_2106 | lpxK | RPC_2106 | RPC_4704 | Lipid A biosynthesis acyltransferase. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.825 |