Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (370 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.996
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.996
RPD_2100
Acetolactate synthase, small subunit.
 
 0.992
RPD_2098
Acetolactate synthase, large subunit.
 
 0.978
RPD_3594
Acetolactate synthase, large subunit; Belongs to the TPP enzyme family.
 
 0.966
RPD_1101
Acetolactate synthase, large subunit; Belongs to the TPP enzyme family.
 
 0.953
RPD_1632
L-threonine ammonia-lyase.
 
 0.952
RPD_2099
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
 
 0.950
RPD_2070
Thiamine pyrophosphate enzyme-like TPP-binding.
  
 0.940
RPD_3688
Thiamine pyrophosphate enzyme-like TPP-binding.
  
 0.940
Your Current Organism:
Rhodopseudomonas palustris BisB5
NCBI taxonomy Id: 316057
Other names: R. palustris BisB5, Rhodopseudomonas palustris str. BisB5, Rhodopseudomonas palustris strain BisB5
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