| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPD_1379 | RPD_2426 | RPD_1379 | RPD_2426 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein. | 0.544 |
| RPD_1379 | aat | RPD_1379 | RPD_2425 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.502 |
| RPD_2424 | aat | RPD_2424 | RPD_2425 | Conserved hypothetical protein. | Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.503 |
| RPD_2426 | RPD_1379 | RPD_2426 | RPD_1379 | Conserved hypothetical protein. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.544 |
| RPD_2426 | RPD_2428 | RPD_2426 | RPD_2428 | Conserved hypothetical protein. | Signal transduction histidine kinase. | 0.426 |
| RPD_2426 | RPD_2429 | RPD_2426 | RPD_2429 | Conserved hypothetical protein. | Response regulator receiver. | 0.423 |
| RPD_2426 | RPD_2430 | RPD_2426 | RPD_2430 | Conserved hypothetical protein. | Multi-sensor signal transduction histidine kinase. | 0.434 |
| RPD_2426 | aat | RPD_2426 | RPD_2425 | Conserved hypothetical protein. | Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.558 |
| RPD_2428 | RPD_2426 | RPD_2428 | RPD_2426 | Signal transduction histidine kinase. | Conserved hypothetical protein. | 0.426 |
| RPD_2428 | RPD_2429 | RPD_2428 | RPD_2429 | Signal transduction histidine kinase. | Response regulator receiver. | 0.971 |
| RPD_2428 | RPD_2430 | RPD_2428 | RPD_2430 | Signal transduction histidine kinase. | Multi-sensor signal transduction histidine kinase. | 0.971 |
| RPD_2428 | RPD_2431 | RPD_2428 | RPD_2431 | Signal transduction histidine kinase. | Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.679 |
| RPD_2428 | aat | RPD_2428 | RPD_2425 | Signal transduction histidine kinase. | Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.641 |
| RPD_2428 | aroQ | RPD_2428 | RPD_2433 | Signal transduction histidine kinase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.463 |
| RPD_2429 | RPD_2426 | RPD_2429 | RPD_2426 | Response regulator receiver. | Conserved hypothetical protein. | 0.423 |
| RPD_2429 | RPD_2428 | RPD_2429 | RPD_2428 | Response regulator receiver. | Signal transduction histidine kinase. | 0.971 |
| RPD_2429 | RPD_2430 | RPD_2429 | RPD_2430 | Response regulator receiver. | Multi-sensor signal transduction histidine kinase. | 0.977 |
| RPD_2429 | RPD_2431 | RPD_2429 | RPD_2431 | Response regulator receiver. | Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.692 |
| RPD_2429 | aat | RPD_2429 | RPD_2425 | Response regulator receiver. | Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.592 |
| RPD_2429 | aroQ | RPD_2429 | RPD_2433 | Response regulator receiver. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.484 |