node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPD_2100 | RPD_2779 | RPD_2100 | RPD_2779 | Acetolactate synthase, small subunit. | Protein of unknown function DUF815. | 0.407 |
RPD_2100 | ilvC | RPD_2100 | RPD_2102 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.997 |
RPD_2774 | RPD_2775 | RPD_2774 | RPD_2775 | Phytoene synthase. | Protein of unknown function DUF498. | 0.946 |
RPD_2774 | RPD_2779 | RPD_2774 | RPD_2779 | Phytoene synthase. | Protein of unknown function DUF815. | 0.544 |
RPD_2774 | secD | RPD_2774 | RPD_2777 | Phytoene synthase. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.837 |
RPD_2774 | secF | RPD_2774 | RPD_2776 | Phytoene synthase. | Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.875 |
RPD_2774 | yajC | RPD_2774 | RPD_2778 | Phytoene synthase. | Protein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.671 |
RPD_2775 | RPD_2774 | RPD_2775 | RPD_2774 | Protein of unknown function DUF498. | Phytoene synthase. | 0.946 |
RPD_2775 | RPD_2779 | RPD_2775 | RPD_2779 | Protein of unknown function DUF498. | Protein of unknown function DUF815. | 0.581 |
RPD_2775 | RPD_3885 | RPD_2775 | RPD_3885 | Protein of unknown function DUF498. | Transcriptional regulator, MarR family. | 0.451 |
RPD_2775 | secD | RPD_2775 | RPD_2777 | Protein of unknown function DUF498. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.838 |
RPD_2775 | secF | RPD_2775 | RPD_2776 | Protein of unknown function DUF498. | Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.875 |
RPD_2775 | yajC | RPD_2775 | RPD_2778 | Protein of unknown function DUF498. | Protein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.672 |
RPD_2779 | RPD_2100 | RPD_2779 | RPD_2100 | Protein of unknown function DUF815. | Acetolactate synthase, small subunit. | 0.407 |
RPD_2779 | RPD_2774 | RPD_2779 | RPD_2774 | Protein of unknown function DUF815. | Phytoene synthase. | 0.544 |
RPD_2779 | RPD_2775 | RPD_2779 | RPD_2775 | Protein of unknown function DUF815. | Protein of unknown function DUF498. | 0.581 |
RPD_2779 | RPD_2780 | RPD_2779 | RPD_2780 | Protein of unknown function DUF815. | Conserved hypothetical protein. | 0.554 |
RPD_2779 | RPD_3885 | RPD_2779 | RPD_3885 | Protein of unknown function DUF815. | Transcriptional regulator, MarR family. | 0.428 |
RPD_2779 | RPD_4102 | RPD_2779 | RPD_4102 | Protein of unknown function DUF815. | Prephenate dehydrogenase. | 0.533 |
RPD_2779 | ilvC | RPD_2779 | RPD_2102 | Protein of unknown function DUF815. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.537 |