| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPD_0002 | RPD_2953 | RPD_0002 | RPD_2953 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | 0.987 |
| RPD_0002 | RPD_2991 | RPD_0002 | RPD_2991 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.606 |
| RPD_0002 | recF | RPD_0002 | RPD_0003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.931 |
| RPD_0002 | recO | RPD_0002 | RPD_2654 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.443 |
| RPD_0002 | rnpA | RPD_0002 | RPD_0068 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.578 |
| RPD_0171 | RPD_2953 | RPD_0171 | RPD_2953 | Glutathione S-transferase-like. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | 0.687 |
| RPD_0171 | recO | RPD_0171 | RPD_2654 | Glutathione S-transferase-like. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.673 |
| RPD_0171 | rnpA | RPD_0171 | RPD_0068 | Glutathione S-transferase-like. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.424 |
| RPD_2953 | RPD_0002 | RPD_2953 | RPD_0002 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.987 |
| RPD_2953 | RPD_0171 | RPD_2953 | RPD_0171 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | Glutathione S-transferase-like. | 0.687 |
| RPD_2953 | RPD_2954 | RPD_2953 | RPD_2954 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | CDP-alcohol phosphatidyltransferase. | 0.696 |
| RPD_2953 | RPD_2991 | RPD_2953 | RPD_2991 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.755 |
| RPD_2953 | ppk | RPD_2953 | RPD_2952 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.702 |
| RPD_2953 | recF | RPD_2953 | RPD_0003 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.781 |
| RPD_2953 | recO | RPD_2953 | RPD_2654 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.773 |
| RPD_2953 | rnpA | RPD_2953 | RPD_0068 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.676 |
| RPD_2953 | rpmE | RPD_2953 | RPD_4343 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | LSU ribosomal protein L31P; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.805 |
| RPD_2953 | rpmJ | RPD_2953 | RPD_1398 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | LSU ribosomal protein L36P; Belongs to the bacterial ribosomal protein bL36 family. | 0.716 |
| RPD_2954 | RPD_2953 | RPD_2954 | RPD_2953 | CDP-alcohol phosphatidyltransferase. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. | 0.696 |
| RPD_2954 | ppk | RPD_2954 | RPD_2952 | CDP-alcohol phosphatidyltransferase. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.533 |