| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPD_1104 | RPD_2245 | RPD_1104 | RPD_2245 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine synthase (B12-independent). | 0.913 |
| RPD_1104 | RPD_2495 | RPD_1104 | RPD_2495 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Homoserine dehydrogenase. | 0.852 |
| RPD_1104 | RPD_2557 | RPD_1104 | RPD_2557 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Cystathionine beta-lyase. | 0.939 |
| RPD_1104 | RPD_3541 | RPD_1104 | RPD_3541 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
| RPD_1104 | ahcY | RPD_1104 | RPD_1597 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.909 |
| RPD_1104 | metK | RPD_1104 | RPD_1596 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.916 |
| RPD_1104 | metZ | RPD_1104 | RPD_0903 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.929 |
| RPD_1339 | RPD_2245 | RPD_1339 | RPD_2245 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine synthase (B12-independent). | 0.913 |
| RPD_1339 | RPD_2495 | RPD_1339 | RPD_2495 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Homoserine dehydrogenase. | 0.852 |
| RPD_1339 | RPD_2557 | RPD_1339 | RPD_2557 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Cystathionine beta-lyase. | 0.939 |
| RPD_1339 | RPD_3541 | RPD_1339 | RPD_3541 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
| RPD_1339 | ahcY | RPD_1339 | RPD_1597 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.909 |
| RPD_1339 | metK | RPD_1339 | RPD_1596 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.916 |
| RPD_1339 | metZ | RPD_1339 | RPD_0903 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.930 |
| RPD_1733 | RPD_3540 | RPD_1733 | RPD_3540 | Glycine cleavage system T protein. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.939 |
| RPD_1733 | RPD_3541 | RPD_1733 | RPD_3541 | Glycine cleavage system T protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.965 |
| RPD_2245 | RPD_1104 | RPD_2245 | RPD_1104 | Methionine synthase (B12-independent). | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.913 |
| RPD_2245 | RPD_1339 | RPD_2245 | RPD_1339 | Methionine synthase (B12-independent). | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.913 |
| RPD_2245 | RPD_2495 | RPD_2245 | RPD_2495 | Methionine synthase (B12-independent). | Homoserine dehydrogenase. | 0.884 |
| RPD_2245 | RPD_2557 | RPD_2245 | RPD_2557 | Methionine synthase (B12-independent). | Cystathionine beta-lyase. | 0.946 |