| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPD_1853 | apt | RPD_1853 | RPD_4212 | Class II aldolase/adducin-like. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.541 |
| RPD_1853 | mtnA | RPD_1853 | RPD_4407 | Class II aldolase/adducin-like. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.783 |
| RPD_1853 | mtnP | RPD_1853 | RPD_4408 | Class II aldolase/adducin-like. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.473 |
| RPD_1853 | tal | RPD_1853 | RPD_3474 | Class II aldolase/adducin-like. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.555 |
| RPD_2420 | mtnP | RPD_2420 | RPD_4408 | Alpha/beta hydrolase fold-3. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.708 |
| RPD_3877 | apt | RPD_3877 | RPD_4212 | Protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.909 |
| RPD_3877 | mtnA | RPD_3877 | RPD_4407 | Protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.902 |
| RPD_3877 | mtnP | RPD_3877 | RPD_4408 | Protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.905 |
| RPD_4409 | RPD_4410 | RPD_4409 | RPD_4410 | Iron-containing alcohol dehydrogenase. | AMP-dependent synthetase and ligase. | 0.698 |
| RPD_4409 | guaA | RPD_4409 | RPD_2269 | Iron-containing alcohol dehydrogenase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.500 |
| RPD_4409 | mtnA | RPD_4409 | RPD_4407 | Iron-containing alcohol dehydrogenase. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.498 |
| RPD_4409 | mtnP | RPD_4409 | RPD_4408 | Iron-containing alcohol dehydrogenase. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.549 |
| RPD_4409 | tal | RPD_4409 | RPD_3474 | Iron-containing alcohol dehydrogenase. | Glucose-6-phosphate isomerase / transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.483 |
| RPD_4410 | RPD_4409 | RPD_4410 | RPD_4409 | AMP-dependent synthetase and ligase. | Iron-containing alcohol dehydrogenase. | 0.698 |
| RPD_4410 | mtnP | RPD_4410 | RPD_4408 | AMP-dependent synthetase and ligase. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.498 |
| apt | RPD_1853 | RPD_4212 | RPD_1853 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Class II aldolase/adducin-like. | 0.541 |
| apt | RPD_3877 | RPD_4212 | RPD_3877 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.909 |
| apt | guaA | RPD_4212 | RPD_2269 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.905 |
| apt | guaB | RPD_4212 | RPD_2264 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.487 |
| apt | mtnA | RPD_4212 | RPD_4407 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.649 |