| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Geob_2372 | dinB | Geob_2372 | Geob_3171 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.681 |
| Geob_2372 | dnaE | Geob_2372 | Geob_3293 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, alpha subunit. | 0.689 |
| Geob_2372 | dnaN | Geob_2372 | Geob_0002 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.978 |
| Geob_2372 | dnaX | Geob_2372 | Geob_0378 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.662 |
| Geob_2372 | holA | Geob_2372 | Geob_2173 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, delta subunit. | 0.589 |
| Geob_2372 | holB | Geob_2372 | Geob_2151 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, delta-prime subunit. | 0.613 |
| Geob_2372 | ligD | Geob_2372 | Geob_0336 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA ligase D, ATP-dependent. | 0.940 |
| Geob_2372 | mutS-1 | Geob_2372 | Geob_2761 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA mismatch repair ATPase MutS-1; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.911 |
| Geob_2372 | polA | Geob_2372 | Geob_1408 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.836 |
| dinB | Geob_2372 | Geob_3171 | Geob_2372 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.681 |
| dinB | dnaE | Geob_3171 | Geob_3293 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, alpha subunit. | 0.815 |
| dinB | dnaN | Geob_3171 | Geob_0002 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.941 |
| dinB | ligD | Geob_3171 | Geob_0336 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA ligase D, ATP-dependent. | 0.600 |
| dinB | mutS-1 | Geob_3171 | Geob_2761 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA mismatch repair ATPase MutS-1; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.543 |
| dinB | polA | Geob_3171 | Geob_1408 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.681 |
| dnaA | dnaN | Geob_0001 | Geob_0002 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.940 |
| dnaE | Geob_2372 | Geob_3293 | Geob_2372 | DNA polymerase III, alpha subunit. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.689 |
| dnaE | dinB | Geob_3293 | Geob_3171 | DNA polymerase III, alpha subunit. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.815 |
| dnaE | dnaN | Geob_3293 | Geob_0002 | DNA polymerase III, alpha subunit. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
| dnaE | dnaX | Geob_3293 | Geob_0378 | DNA polymerase III, alpha subunit. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
