Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Geob_1175Hypothetical protein. (243 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.951
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.892
grpE
DnaJ adenine nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...]
  
 
 0.868
Geob_3146
Flavin oxidoreductase, PfaD family, putative.
  
 
 0.838
Geob_0651
SAM-dependent methyltransferase and glycosyltransferase, TPR domain-containing.
   
 0.813
bamH-1
benzoyl-CoA reductase electron transfer protein, putative.
   
  0.809
Geob_3236
Long-chain acyl-CoA synthetase; Acyl-(acyl carrier protein) ligase, acyl carrier, (acyl)-sn-glycerol-3-phosphate acyltransferase fusion protein.
  
 0.805
groEL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.780
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.750
Geob_1269
Ankyrin repeat protein.
    
 0.736
Your Current Organism:
Geobacter daltonii
NCBI taxonomy Id: 316067
Other names: G. daltonii FRC-32, Geobacter daltonii FRC-32, Geobacter daltonii str. FRC-32, Geobacter daltonii strain FRC-32, Geobacter sp. FRC-32
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