node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Geob_1361 | queE | Geob_1361 | Geob_2831 | (R)-2-hydroxyacyl-CoA dehydratase. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.492 |
Geob_2717 | queC | Geob_2717 | Geob_0700 | 7-cyano-7-carbaguanine synthetase-related protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-carbaguanine synthetase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.926 |
Geob_2717 | queD | Geob_2717 | Geob_2832 | 7-cyano-7-carbaguanine synthetase-related protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.929 |
Geob_2717 | queE | Geob_2717 | Geob_2831 | 7-cyano-7-carbaguanine synthetase-related protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.994 |
Geob_2829 | Geob_2830 | Geob_2829 | Geob_2830 | NUDIX hydrolase, MutT family; Belongs to the Nudix hydrolase family. | Creatinine amidohydrolase superfamily protein. | 0.455 |
Geob_2829 | queD | Geob_2829 | Geob_2832 | NUDIX hydrolase, MutT family; Belongs to the Nudix hydrolase family. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.482 |
Geob_2829 | queE | Geob_2829 | Geob_2831 | NUDIX hydrolase, MutT family; Belongs to the Nudix hydrolase family. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.491 |
Geob_2830 | Geob_2829 | Geob_2830 | Geob_2829 | Creatinine amidohydrolase superfamily protein. | NUDIX hydrolase, MutT family; Belongs to the Nudix hydrolase family. | 0.455 |
Geob_2830 | Geob_2833 | Geob_2830 | Geob_2833 | Creatinine amidohydrolase superfamily protein. | Sensor histidine kinase response receiver, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c, REC. | 0.512 |
Geob_2830 | queD | Geob_2830 | Geob_2832 | Creatinine amidohydrolase superfamily protein. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.817 |
Geob_2830 | queE | Geob_2830 | Geob_2831 | Creatinine amidohydrolase superfamily protein. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.827 |
Geob_2833 | Geob_2830 | Geob_2833 | Geob_2830 | Sensor histidine kinase response receiver, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c, REC. | Creatinine amidohydrolase superfamily protein. | 0.512 |
Geob_2833 | queD | Geob_2833 | Geob_2832 | Sensor histidine kinase response receiver, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c, REC. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.518 |
Geob_2833 | queE | Geob_2833 | Geob_2831 | Sensor histidine kinase response receiver, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c, REC. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.516 |
guaA | purF | Geob_2182 | Geob_2890 | Guanosine-5'-monophosphate synthetase; Catalyzes the synthesis of GMP from XMP. | Glutamine--phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.797 |
guaA | queD | Geob_2182 | Geob_2832 | Guanosine-5'-monophosphate synthetase; Catalyzes the synthesis of GMP from XMP. | 6-carboxy-5,6,7,8-tetrahydropterin synthase. | 0.472 |
guaA | queE | Geob_2182 | Geob_2831 | Guanosine-5'-monophosphate synthetase; Catalyzes the synthesis of GMP from XMP. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.514 |
purF | guaA | Geob_2890 | Geob_2182 | Glutamine--phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | Guanosine-5'-monophosphate synthetase; Catalyzes the synthesis of GMP from XMP. | 0.797 |
purF | queE | Geob_2890 | Geob_2831 | Glutamine--phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 7-carboxy-7-carbaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.524 |
queC | Geob_2717 | Geob_0700 | Geob_2717 | 7-cyano-7-carbaguanine synthetase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-carbaguanine synthetase-related protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.926 |