Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Geob_2863GIY-YIG domain nuclease, putative. (289 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.918
Geob_2864
Hypothetical protein.
       0.773
Geob_2862
Hypothetical protein.
       0.714
Geob_2866
Hypothetical protein.
 
     0.574
pcrA
ATP-dependent DNA helicase PcrA.
  
  
 0.571
rep
ATP-dependent DNA helicase Rep.
  
  
 0.571
Geob_2867
Type I restriction-modification system, DNA specificity subunit.
       0.558
Geob_2868
Type I restriction-modification system, DNA adenine N6-methyltransferase subunit.
       0.558
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
  
 0.555
mutM-2
formamidopyrimidine-DNA glycosylase.
  
  
 0.554
Your Current Organism:
Geobacter daltonii
NCBI taxonomy Id: 316067
Other names: G. daltonii FRC-32, Geobacter daltonii FRC-32, Geobacter daltonii str. FRC-32, Geobacter daltonii strain FRC-32, Geobacter sp. FRC-32
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