| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Geob_2948 | argG | Geob_2948 | Geob_1124 | Glutamine amidotransferase, asparagine synthetase-related. | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.916 |
| Geob_2948 | purA | Geob_2948 | Geob_0846 | Glutamine amidotransferase, asparagine synthetase-related. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.915 |
| Geob_2948 | pyrB | Geob_2948 | Geob_3264 | Glutamine amidotransferase, asparagine synthetase-related. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.928 |
| argG | Geob_2948 | Geob_1124 | Geob_2948 | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Glutamine amidotransferase, asparagine synthetase-related. | 0.916 |
| argG | carA | Geob_1124 | Geob_3266 | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.926 |
| argG | carB | Geob_1124 | Geob_3271 | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.994 |
| argG | purA | Geob_1124 | Geob_0846 | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.934 |
| argG | pyrB | Geob_1124 | Geob_3264 | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.915 |
| carA | argG | Geob_3266 | Geob_1124 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.926 |
| carA | carB | Geob_3266 | Geob_3271 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | 0.999 |
| carA | purA | Geob_3266 | Geob_0846 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.472 |
| carA | pyrB | Geob_3266 | Geob_3264 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | Geob_3266 | Geob_3265 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
| carA | pyrD | Geob_3266 | Geob_2780 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.952 |
| carA | pyrE | Geob_3266 | Geob_2889 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.938 |
| carA | pyrF | Geob_3266 | Geob_2402 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.933 |
| carA | pyrR | Geob_3266 | Geob_3263 | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrimidine operon regulator and uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.898 |
| carB | argG | Geob_3271 | Geob_1124 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Argininosuccinate synthetase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.994 |
| carB | carA | Geob_3271 | Geob_3266 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Carbamyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
| carB | purA | Geob_3271 | Geob_0846 | Carbamyl-phosphate synthase, large subunit, glutamine-dependent; Belongs to the CarB family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.783 |