| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Geob_0481 | folK | Geob_0481 | Geob_0909 | Metal-dependent hydrolase, beta-lactamase superfamily II. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.900 |
| Geob_0481 | folP | Geob_0481 | Geob_3422 | Metal-dependent hydrolase, beta-lactamase superfamily II. | Dihydropteroate synthase. | 0.900 |
| Geob_1294 | folC | Geob_1294 | Geob_1868 | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.485 |
| Geob_1294 | folK | Geob_1294 | Geob_0909 | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.841 |
| Geob_1294 | folP | Geob_1294 | Geob_3422 | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | Dihydropteroate synthase. | 0.982 |
| Geob_1294 | trpG | Geob_1294 | Geob_3439 | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | Anthranilate synthase, glutamine amidotransferase subunit. | 0.999 |
| dacA-2 | folP | Geob_3421 | Geob_3422 | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Dihydropteroate synthase. | 0.696 |
| dacA-2 | ftsH-2 | Geob_3421 | Geob_3423 | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Cell division ATP-dependent zinc protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.660 |
| dacA-2 | glmM | Geob_3421 | Geob_3419 | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.876 |
| dnaK | folP | Geob_1107 | Geob_3422 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Dihydropteroate synthase. | 0.773 |
| dnaK | ftsH-2 | Geob_1107 | Geob_3423 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division ATP-dependent zinc protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.727 |
| folC | Geob_1294 | Geob_1868 | Geob_1294 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | 0.485 |
| folC | folK | Geob_1868 | Geob_0909 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.777 |
| folC | folP | Geob_1868 | Geob_3422 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase. | 0.997 |
| folC | rdgB | Geob_1868 | Geob_3020 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Xanthosine/inosine-5'-triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.562 |
| folK | Geob_0481 | Geob_0909 | Geob_0481 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Metal-dependent hydrolase, beta-lactamase superfamily II. | 0.900 |
| folK | Geob_1294 | Geob_0909 | Geob_1294 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Pyridoxal-5'-phosphate-dependent chorismate-binding enzyme, putative. | 0.841 |
| folK | folC | Geob_0909 | Geob_1868 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.777 |
| folK | folP | Geob_0909 | Geob_3422 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase. | 0.999 |
| folK | rdgB | Geob_0909 | Geob_3020 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Xanthosine/inosine-5'-triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.685 |