STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Haur_0263TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase-cyclodeaminase; Formiminotransferase domain protein; Formiminotransferase domain protein; KEGG: aba:Acid345_2130 formiminotransferase-like. (495 aa)    
Predicted Functional Partners:
hutI
KEGG: sth:STH3191 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
  0.964
Haur_3632
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase.
 
 
 0.948
fhs
PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: rrs:RoseRS_0219 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.940
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.939
Haur_4470
PFAM: Formiminotransferase-cyclodeaminase; KEGG: rrs:RoseRS_4575 formiminotransferase-cyclodeaminase.
 
 
 
0.935
Haur_2544
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.932
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.926
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.916
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
    
 0.912
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
 0.908
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.