STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Haur_0603TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: rrs:RoseRS_4541 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (435 aa)    
Predicted Functional Partners:
Haur_3166
KEGG: ppd:Ppro_2253 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
 
 0.997
Haur_4053
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; KEGG: ath:AT4G30000 dihydropterin pyrophosphokinase, putative / dihydropteroate synthase, putative / DHPS, putative; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
  
 0.809
folE
PFAM: GTP cyclohydrolase I; KEGG: rrs:RoseRS_0705 GTP cyclohydrolase I.
  
  
 0.626
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
  
 0.565
murF-2
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the MurCDEF family. MurF subfamily.
 
   
 0.542
Haur_4975
PFAM: protein of unknown function UPF0079; KEGG: rrs:RoseRS_4357 protein of unknown function UPF0079.
 
    0.537
Haur_0604
PFAM: response regulator receiver; KEGG: ter:Tery_4000 response regulator receiver protein.
       0.529
Haur_0605
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3999 adenylate/guanylate cyclase.
       0.529
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
   
 0.513
Haur_0606
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: rca:Rcas_2639 multi-sensor signal transduction histidine kinase.
       0.507
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.