node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Haur_1193 | mutM | Haur_1193 | Haur_1194 | KEGG: rrs:RoseRS_3053 N-acetylmuramoyl-L-alanine amidase, family 2. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.594 |
Haur_2402 | Haur_4286 | Haur_2402 | Haur_4286 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | 0.908 |
Haur_2402 | dinG | Haur_2402 | Haur_3224 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | 0.452 |
Haur_2402 | mutM | Haur_2402 | Haur_1194 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.585 |
Haur_2402 | polA | Haur_2402 | Haur_0069 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.551 |
Haur_4046 | mutM | Haur_4046 | Haur_1194 | Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: rrs:RoseRS_0529 helix-turn-helix domain protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.532 |
Haur_4286 | Haur_2402 | Haur_4286 | Haur_2402 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | 0.908 |
Haur_4286 | dinG | Haur_4286 | Haur_3224 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | 0.452 |
Haur_4286 | mutM | Haur_4286 | Haur_1194 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.585 |
Haur_4286 | polA | Haur_4286 | Haur_0069 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.551 |
coaE | mutM | Haur_2728 | Haur_1194 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.977 |
coaE | polA | Haur_2728 | Haur_0069 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.719 |
dinG | Haur_2402 | Haur_3224 | Haur_2402 | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | 0.452 |
dinG | Haur_4286 | Haur_3224 | Haur_4286 | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD. | 0.452 |
dinG | mutM | Haur_3224 | Haur_1194 | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.565 |
dinG | polA | Haur_3224 | Haur_0069 | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.974 |
dinG | uvrC | Haur_3224 | Haur_0063 | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.481 |
mutM | Haur_1193 | Haur_1194 | Haur_1193 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | KEGG: rrs:RoseRS_3053 N-acetylmuramoyl-L-alanine amidase, family 2. | 0.594 |
mutM | Haur_2402 | Haur_1194 | Haur_2402 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. | 0.585 |
mutM | Haur_4046 | Haur_1194 | Haur_4046 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: rrs:RoseRS_0529 helix-turn-helix domain protein. | 0.532 |