STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Haur_2402DNA-(apurinic or apyrimidinic site) lyase; KEGG: cya:CYA_0846 base excision DNA repair protein, HhH-GPD family; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop. (222 aa)    
Predicted Functional Partners:
Haur_4286
HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: dge:Dgeo_2290 HhH-GPD.
  
  
 
0.908
Haur_2403
SMART: Integrin alpha beta-propellor repeat protein; KEGG: sde:Sde_2598 PAS/PAC sensor signal transduction histidine kinase.
       0.610
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
   
  
 0.585
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.551
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
  
 
 0.534
hflX
GTP1/OBG protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
    
 0.513
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
  
  
 0.452
Haur_4013
PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: rca:Rcas_0007 PHP domain protein.
     
 0.445
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
    0.442
Haur_2404
PFAM: conserved hypothetical protein; KEGG: rfr:Rfer_3142 conserved hypothetical protein 730; Belongs to the LOG family.
       0.427
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
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