node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Haur_1744 | Haur_3549 | Haur_1744 | Haur_3549 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.997 |
Haur_1744 | Haur_3550 | Haur_1744 | Haur_3550 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | 0.887 |
Haur_1744 | hemA | Haur_1744 | Haur_3544 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.769 |
Haur_1744 | hemC | Haur_1744 | Haur_3548 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.990 |
Haur_1744 | hemE | Haur_1744 | Haur_3546 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.932 |
Haur_1744 | hemL | Haur_1744 | Haur_3551 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: rrs:RoseRS_1753 glutamate-1-semialdehyde-2,1-aminomutase. | 0.611 |
Haur_3156 | Haur_3549 | Haur_3156 | Haur_3549 | PFAM: aminotransferase class-III; KEGG: hch:HCH_06567 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.466 |
Haur_3156 | Haur_3550 | Haur_3156 | Haur_3550 | PFAM: aminotransferase class-III; KEGG: hch:HCH_06567 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | 0.877 |
Haur_3156 | hemA | Haur_3156 | Haur_3544 | PFAM: aminotransferase class-III; KEGG: hch:HCH_06567 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.838 |
Haur_3156 | hemC | Haur_3156 | Haur_3548 | PFAM: aminotransferase class-III; KEGG: hch:HCH_06567 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.867 |
Haur_3545 | hemA | Haur_3545 | Haur_3544 | PFAM: Chlorite dismutase; KEGG: rrs:RoseRS_1747 chlorite dismutase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.677 |
Haur_3545 | hemC | Haur_3545 | Haur_3548 | PFAM: Chlorite dismutase; KEGG: rrs:RoseRS_1747 chlorite dismutase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.402 |
Haur_3545 | hemE | Haur_3545 | Haur_3546 | PFAM: Chlorite dismutase; KEGG: rrs:RoseRS_1747 chlorite dismutase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.635 |
Haur_3545 | hemH | Haur_3545 | Haur_3547 | PFAM: Chlorite dismutase; KEGG: rrs:RoseRS_1747 chlorite dismutase. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.781 |
Haur_3549 | Haur_1744 | Haur_3549 | Haur_1744 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.997 |
Haur_3549 | Haur_3156 | Haur_3549 | Haur_3156 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: aminotransferase class-III; KEGG: hch:HCH_06567 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.466 |
Haur_3549 | Haur_3550 | Haur_3549 | Haur_3550 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family. | 0.994 |
Haur_3549 | hemA | Haur_3549 | Haur_3544 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.884 |
Haur_3549 | hemC | Haur_3549 | Haur_3548 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Haur_3549 | hemE | Haur_3549 | Haur_3546 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.944 |