STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (305 aa)    
Predicted Functional Partners:
Haur_4659
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.994
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.992
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.927
Haur_1699
Flavodoxin; KEGG: mem:Memar_1824 flavodoxin.
    
 0.923
Haur_3097
KEGG: rca:Rcas_1420 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase.
   
 
 0.917
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.796
Haur_3545
PFAM: Chlorite dismutase; KEGG: rrs:RoseRS_1747 chlorite dismutase.
 
  
 0.781
Haur_2794
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: rrs:RoseRS_0088 amine oxidase.
  
  
 0.766
Haur_3550
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: rrs:RoseRS_1752 porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.652
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.647
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
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