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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Haur_4635Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (332 aa)    
Predicted Functional Partners:
Haur_2591
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; KEGG: gtn:GTNG_2307 2-oxoisovalerate dehydrogenase alpha subunit.
 0.999
pdhA
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
Haur_4636
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rrs:RoseRS_1726 dihydrolipoyllysine-residue succinyltransferase.
 0.999
Haur_4513
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rca:Rcas_2104 dihydrolipoamide dehydrogenase.
 0.996
Haur_2593
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rca:Rcas_2804 catalytic domain of components of various dehydrogenase complexes.
 0.985
Haur_3049
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: ter:Tery_3348 pyridine nucleotide-disulphide oxidoreductase dimerisation region.
 0.942
Haur_2775
E3 binding domain protein; PFAM: biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bcl:ABC2449 branched-chain alpha-keto acid dehydrogenase E2 component.
 
 0.939
Haur_0037
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rrs:RoseRS_1551 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.929
Haur_2602
KEGG: rrs:RoseRS_1428 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.923
Haur_0038
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: rca:Rcas_2309 thiamine pyrophosphate protein domain protein TPP-binding.
     
 0.913
Your Current Organism:
Herpetosiphon aurantiacus
NCBI taxonomy Id: 316274
Other names: H. aurantiacus DSM 785, Herpetosiphon aurantiacus ATCC 23779, Herpetosiphon aurantiacus DSM 785
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