STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxD-2UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (347 aa)    
Predicted Functional Partners:
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
 
 0.987
lpxB
Lipid-A-disaccharide synthase [CAZy:GT19]; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.986
CAK27243.1
Cyanobacteria-specific protein related to lipidA disaccharide synthetase; Cell envelope biogenesis, outer membrane.
 
 
 0.969
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Cell envelope biogenesis, outer membrane.
  
  
 
0.929
kpsF
Polysialic acid capsule expression protein; Cell envelope biogenesis, outer membrane; Belongs to the SIS family. GutQ/KpsF subfamily.
 
  
 0.831
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.779
CAK27903.1
Predicted hydrolase of the HAD superfamily.
       0.778
CAK27904.1
Conserved hypothetical protein.
       0.778
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Cell envelope biogenesis, outer membrane; Belongs to the KdsB family.
 
   
 0.776
CAK28722.1
Predicted outer membrane protein / surface antigene; Cell envelope biogenesis, outer membrane.
 
  
 0.771
Your Current Organism:
Synechococcus sp. RCC307
NCBI taxonomy Id: 316278
Other names: S. sp. RCC307, Synechococcus sp. MINSyn016-15m-01 substr. AC6A1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.