Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANZ13966.1Peptidase. (522 aa)    
Predicted Functional Partners:
ANZ13686.1
Polyketide synthase.
 
 0.650
ANZ13965.1
Phosphoserine phosphatase.
 
   
 0.483
ANZ13721.1
Alpha/beta hydrolase family.
  
     0.463
ANZ21057.1
Acyltransferase family protein.
 
 0.446
ANZ15007.1
Bifunctional P-450:NADPH-P450 reductase 1.
  
 0.423
ANZ20612.1
Polyketide synthase family protein.
  
 0.421
nucS
Endonuclease NucS; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.409
ANZ16991.1
Ankyrin-like protein.
 
 0.400
Your Current Organism:
Streptomyces noursei
NCBI taxonomy Id: 316284
Other names: S. noursei ATCC 11455, Streptomyces noursei ATCC 11455, Streptomyces noursei str. ATCC 11455, Streptomyces noursei strain ATCC 11455
Server load: low (24%) [HD]