Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANZ14013.1Transcriptional regulator, TetR family. (210 aa)    
Predicted Functional Partners:
ANZ14012.1
DNA-binding protein.
       0.505
ANZ19135.1
Epimerase family protein.
  
    0.490
ideR
Iron (metal) dependent repressor, DtxR family.
   
    0.477
ANZ14014.1
Hypothetical protein.
       0.476
ANZ14015.1
Protein of unknown function DUF302.
       0.476
ANZ14016.1
Hydroxylase.
       0.476
ANZ15722.1
Helix-turn-helix domain/MarR family.
  
    0.409
ANZ16943.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.407
Your Current Organism:
Streptomyces noursei
NCBI taxonomy Id: 316284
Other names: S. noursei ATCC 11455, Streptomyces noursei ATCC 11455, Streptomyces noursei str. ATCC 11455, Streptomyces noursei strain ATCC 11455
Server load: low (34%) [HD]