STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANZ19432.1cob(I)yrinic acid a,c-diamide adenosyltransferase. (199 aa)    
Predicted Functional Partners:
cobB
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.998
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.997
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.996
ANZ17644.1
Cobaltochelatase, CobN subunit.
 
  
 0.995
ANZ19150.1
Adenosylcobinamide-phosphate guanylyltransferase; adenosylcobinamide kinase.
 
  
 0.991
cobS
Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.990
chlI
Magnesium-chelatase subunit.
 
   
 0.974
cobM
Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.939
ANZ16245.1
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.934
cobIJ
Cobalamin biosynthesis protein CobIJ.
 
   
 0.928
Your Current Organism:
Streptomyces noursei
NCBI taxonomy Id: 316284
Other names: S. noursei ATCC 11455, Streptomyces noursei ATCC 11455, Streptomyces noursei str. ATCC 11455, Streptomyces noursei strain ATCC 11455
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