STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdAMetallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (244 aa)    
Predicted Functional Partners:
ETK34703.1
Histidine kinase.
  
 
 0.880
ETK31512.1
Histidine kinase.
  
 
 0.880
ETK31469.1
Hypothetical protein.
  
 
 0.880
ETK33409.1
Adenylate cyclase.
     
 0.872
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.868
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.851
ETK35648.1
Hypothetical protein.
     
 0.846
ETK31022.1
Nucleotide pyrophosphohydrolase.
  
  
  0.845
ETK30917.1
Histidine kinase.
    
 0.826
ETK33106.1
PAS containing protein phosphatase 2C.
    
 0.767
Your Current Organism:
Microbispora sp. ATCC PTA5024
NCBI taxonomy Id: 316330
Other names: M. sp. ATCC PTA-5024, Microbispora sp. ATCC PTA-5024
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.