STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETK32845.1Hypothetical protein. (195 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.893
ETK37463.1
Hypothetical protein; Belongs to the UPF0337 (CsbD) family.
  
  
 0.839
ETK37085.1
Hypothetical protein.
 
     0.751
ETK38043.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
  0.743
ETK31583.1
Hypothetical protein.
  
     0.705
ETK32119.1
Inosine 5'-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate.
  
 
  0.669
ETK38000.1
Signal transduction protein.
 
   
 0.662
guaB
Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.654
ETK32846.1
Phosphoesterase.
       0.605
ETK32847.1
Hypothetical protein.
       0.509
Your Current Organism:
Microbispora sp. ATCC PTA5024
NCBI taxonomy Id: 316330
Other names: M. sp. ATCC PTA-5024, Microbispora sp. ATCC PTA-5024
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.