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uhpT protein (Escherichia coli K12 DH10B) - STRING interaction network
"uhpT" - Sugar phosphate antiporter in Escherichia coli K12 DH10B
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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uhpTSugar phosphate antiporter; Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate. Can transport glucose-6-phosphate, fructose-6-phosphate and mannose-6-phosphate. Also catalyzes the neutral exchange of internal and external phosphate (463 aa)    
Predicted Functional Partners:
uhpB
Sensory histidine kinase UhpB; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpB functions as a membrane-associated protein kinase that autophosphorylates in response to interaction with UhpC, and subsequently transfers its phosphate group to the response regulator UhpA (PubMed-3038843, PubMed-8349544, PubMed-11053370, PubMed-11739766). Can also dephosphorylate UhpA (PubMed-11053370, PubMed-11739766) (500 aa)
 
 
  0.958
uhpA
DNA-binding transcriptional activator UhpA; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region (196 aa)
 
   
  0.847
uhpC
Regulatory protein UhpC; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpC senses external glucose-6-phosphate and interacts with the histidine kinase UhpB, leading to the stimulation of the autokinase activity of UhpB (439 aa)
 
     
0.685
ygjI
Transporter (477 aa)
   
   
  0.612
glpQ
Glycerophosphodiester phosphodiesterase; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols (358 aa)
 
   
  0.568
glpA
Sn-glycerol-3-phosphate dehydrogenase subunit A; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor (542 aa)
 
   
  0.535
ygjK
Putative glycosyl hydrolase; Glucoside hydrolase that cleaves the alpha-1,3- glucosidic linkage in nigerose. Has very low activity towards maltooligosaccharides, soluble starch, nigerotriose, kojibiose and trehalose (783 aa)
   
          0.497
gmr
RNase II stability modulator; Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antagonized by the diguanylate cyclase YdaM. In vitro has c-di-GMP phosphodiesterase activity. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (661 aa)
     
 
  0.450
ilvB
Acetolactate synthase catalytic subunit (562 aa)
   
        0.422
ilvN
Acetolactate synthase 1 regulatory subunit (96 aa)
              0.412
Your Current Organism:
Escherichia coli K12 DH10B
NCBI taxonomy Id: 316385
Other names: E. coli str. K-12 substr. DH10B, Escherichia coli DH10B, Escherichia coli K12 DH10B, Escherichia coli str. K-12 substr. DH10B, Escherichia coli str. K12 substr. DH10B, Escherichia coli strain K12 substrain DH10B
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