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evgS protein (Escherichia coli K12 W3110) - STRING interaction network
"evgS" - Hybrid sensory histidine kinase in two-component regulatory system with EvgA in Escherichia coli K12 W3110
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
evgSHybrid sensory histidine kinase in two-component regulatory system with EvgA; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals (1197 aa)    
Predicted Functional Partners:
evgA
DNA-binding response regulator in two-component regulatory system with EvgS; Member of the two-component regulatory system EvgS/EvgA. Regulates the expression of emrKY operon and yfdX. Seems also to control expression of at least one other multidrug efflux operon (204 aa)
 
  0.999
aer
Fused signal transducer for aerotaxis sensory component and methyl accepting chemotaxis component; Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a redox sensor to monitor oxygen levels (506 aa)
   
  0.998
phoQ
Sensory histidine kinase in two-compoent regulatory system with PhoP; Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phospho-PhoP, resulting [...] (486 aa)
   
  0.997
atoS
Sensory histidine kinase in two-component regulatory system with AtoC; Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation (608 aa)
   
0.995
arcB
Hybrid sensory histidine kinase in two-component regulatory system with ArcA; Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and Asp-576 (778 aa)
 
0.995
barA
Hybrid sensory histidine kinase, in two-component regulatory system with UvrY; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (918 aa)
 
0.993
yedV
Predicted sensory kinase in two-component regulatory system with YedW; Probable member of a two-component regulatory system YedW/YedV. Activates YedW by phosphorylation (452 aa)
 
0.993
torS
Hybrid sensory histidine kinase in two-component regulatory system with TorR; Member of the two-component regulatory system TorS/TorR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates TorR via a four-step phosphorelay. When TMAO is removed, TorS can dephosphorylate TorR, probably by a reverse phosphorelay involving His-860 and Asp-733 (914 aa)
 
0.993
cusS
Sensory histidine kinase in two-component regulatory system with CusR, senses copper ions; Member of the two-component regulatory system CusS/CusR. Copper ion sensor. Could also be a silver ion sensor. Activates CusR by phosphorylation (480 aa)
 
0.993
baeS
Sensory histidine kinase in two-component regulatory system with BaeR; Member of the two-component regulatory system BaeS/BaeR which responds to envelope stress (PubMed-12354228, PubMed-21317898). Activates expression of periplasmic chaperone spy in response to spheroplast formation, indole and P pili protein PapG overexpression (PubMed-12354228). Activates BaeR by phosphorylation which then activates the mdtABCD (PubMed-12107134) and probably the CRISPR-Cas casABCDE-ygbT-ygbF operons (PubMed-21255106) (467 aa)
   
0.992
Your Current Organism:
Escherichia coli K12 W3110
NCBI taxonomy Id: 316407
Other names: E. coli str. K-12 substr. W3110, Escherichia coli K12 W3110, Escherichia coli W3110, Escherichia coli str. K-12 substr. W3110, Escherichia coli str. K12 substr. W3110, Escherichia coli str. W3110, Escherichia coli strain W3110
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