STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_0859impB/mucB/samB family protein; PFAM: UMUC-like DNA-repair protein; KEGG: ecs:ECs1679 UmuC protein. (450 aa)    
Predicted Functional Partners:
Tcr_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.990
Tcr_0858
UmuD protein. Serine peptidase. MEROPS family S24; PFAM: peptidase S24, S26A and S26B; KEGG: syc:syc0007_d DNA polymerase V; Belongs to the peptidase S24 family.
 
 
 0.974
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.856
Tcr_1234
S24 family peptidase; Represses a number of genes involved in the response to DNA damage (SOS response).
 
 
 0.831
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.787
Tcr_1115
KEGG: vfi:VF1947 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP-like nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Phosphoesterase PHP-like.
  
  
 0.727
Tcr_0762
PFAM: FKBP-type peptidyl-prolyl isomerase-like peptidylprolyl isomerase, FKBP-type; KEGG: mip; peptidyl-prolyl cis-trans isomerase.
  
 
 
 0.718
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
   
 
 0.712
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
   
 
 0.712
Tcr_1026
PFAM: FKBP-type peptidyl-prolyl isomerase-like peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1139 peptidyl-prolyl cis-trans isomerase FklB.
    
 
 0.682
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.