STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_0885N-acetylglucosamine kinase; PFAM: ROK domain containing protein; KEGG: mca:MCA0661 ROK family protein. (301 aa)    
Predicted Functional Partners:
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
  
 0.944
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: aci:ACIAD0101 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.934
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.918
Tcr_1488
Ketohexokinase; PFAM: Rieske [2Fe-2S] region PfkB; KEGG: hsa:3795 ketohexokinase (fructokinase).
  
 
 0.917
Tcr_1796
PFAM: PfkB; KEGG: neu:NE1212 PfkB family of carbohydrate kinase.
  
 
 0.916
fbp
PFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: son:SO3991 fructose-1,6-bisphosphatase.
     
 0.906
Tcr_0884
Conserved hypothetical protein with a SAM-binding domain; KEGG: vfi:VFA0455 hypothetical protein.
       0.773
Tcr_0883
PFAM: protein of unknown function DUF455; KEGG: xcc:XCC0954 hypothetical protein.
       0.747
Tcr_0886
Conserved hypothetical protein; KEGG: tte:TTE1718 thiol-disulfide isomerase and thioredoxins.
       0.623
Tcr_1457
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: gka:GK3126 UDP-N-acetylglucosamine-2-epimerase (5.1.3.-).
 
    
 0.584
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
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