STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (236 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.995
pyrB
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: mca:MCA2333 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.962
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
  
 0.961
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain, oligomerisation Carbamoyl-phosphate synthetase large chain-like MGS-like; KEGG: pae:PA4756 carbamoylphosphate synthetase large subunit; Belongs to the CarB family.
  
  
 0.957
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I Carbamoyl-phosphate synthase, small chain; KEGG: spt:SPA0067 carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
  
 0.943
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.932
surE
3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.915
Tcr_1757
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: pae:PA5177 probable hydrolase.
  
 
  0.901
Tcr_1830
TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: pst:PSPTO5041 dihydroorotase, multifunctional complex type.
  
  
 0.862
Tcr_1889
Dihydroorotase; PFAM: amidohydrolase; KEGG: ftu:FTT1660c dihydroorotase.
  
  
 0.862
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
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