Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_2002Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR LysR, substrate-binding; KEGG: vfi:VF1066 transcriptional regulators, LysR family. (301 aa)    
Predicted Functional Partners:
Tcr_2000
Resistance-Nodulation-Cell Division (RND) superfamily cation efflux transporter; PFAM: acriflavin resistance protein; KEGG: son:SO1882 AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.543
Tcr_2001
RND membrane fusion protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: ilo:IL2305 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.543
Tcr_2003
PFAM: Pirin-like; KEGG: vfi:VF1068 pirin; Belongs to the pirin family.
   
   0.543
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.487
Tcr_1957
PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: pst:PSPTO5123 glutamate synthase, large subunit.
     
 0.466
Tcr_0054
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR LysR, substrate-binding; KEGG: bps:BPSL2866 oxidative stress regulatory protein; Belongs to the LysR transcriptional regulatory family.
  
     0.437
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.422
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
Server load: low (10%) [HD]