Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tcr_2139PFAM: DegT/DnrJ/EryC1/StrS aminotransferase aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO2476 polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family. (394 aa)    
Predicted Functional Partners:
Tcr_1675
PFAM: sugar transferase; KEGG: vpa:VPA1403 putative capsular polysaccharide biosynthesis glycosyltransferase.
  
  
 0.943
Tcr_2140
PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO2477 alcohol dehydrogenase, iron-containing.
 
   
 0.934
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
   0.749
Tcr_1457
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: gka:GK3126 UDP-N-acetylglucosamine-2-epimerase (5.1.3.-).
  
  
 0.548
kdsB2
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
     
 0.545
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
       0.519
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
    0.505
Tcr_1678
KEGG: hhe:HH0675 mannose-1-phosphate guanylyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin region; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.491
Tcr_2142
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.485
Tcr_2135
PFAM: Aldose 1-epimerase; KEGG: neu:NE1003 aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.
       0.481
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
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