STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_2140PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO2477 alcohol dehydrogenase, iron-containing. (357 aa)    
Predicted Functional Partners:
kdsB2
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
    
 0.942
Tcr_2139
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO2476 polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.
 
     0.934
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.676
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.675
Tcr_0626
FAD-linked oxidoreductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding protein of unknown function DUF224, cysteine-rich region FAD linked oxidase-like; KEGG: gvi:glr3436 probable oxidoreductase.
 
  
 0.632
Tcr_2142
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.527
Tcr_0383
Hypothetical protein; PFAM: Heavy metal transport/detoxification protein; KEGG: wsu:WS1451 hypothetical protein.
  
     0.510
kdsB1
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
    
 0.507
Tcr_1709
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase pyruvate flavodoxin/ferredoxin oxidoreductase-like; KEGG: gka:GK1301 2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) alpha subunit.
  
  
 0.495
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.465
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.