node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DFI_01735 | DFI_11185 | GCA_000419625_00798 | GCA_000419625_01688 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.542 |
DFI_01735 | mnmE | GCA_000419625_00798 | GCA_000419625_01731 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.612 |
DFI_01735 | obg | GCA_000419625_00798 | GCA_000419625_00783 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.555 |
DFI_01735 | rplN | GCA_000419625_00798 | GCA_000419625_00697 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.466 |
DFI_01735 | rplU | GCA_000419625_00798 | GCA_000419625_00781 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.574 |
DFI_01735 | rsfS | GCA_000419625_00798 | GCA_000419625_00578 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.592 |
DFI_01735 | truD | GCA_000419625_00798 | GCA_000419625_02662 | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.525 |
DFI_05775 | DFI_11185 | GCA_000419625_02776 | GCA_000419625_01688 | UPF0176 protein DFI_05775; Belongs to the UPF0176 family. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.897 |
DFI_11180 | DFI_11185 | GCA_000419625_01689 | GCA_000419625_01688 | N-acetyltransferase. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.554 |
DFI_11180 | trmB | GCA_000419625_01689 | GCA_000419625_01692 | N-acetyltransferase. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.512 |
DFI_11185 | DFI_01735 | GCA_000419625_01688 | GCA_000419625_00798 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.542 |
DFI_11185 | DFI_05775 | GCA_000419625_01688 | GCA_000419625_02776 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | UPF0176 protein DFI_05775; Belongs to the UPF0176 family. | 0.897 |
DFI_11185 | DFI_11180 | GCA_000419625_01688 | GCA_000419625_01689 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | N-acetyltransferase. | 0.554 |
DFI_11185 | mnmE | GCA_000419625_01688 | GCA_000419625_01731 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.542 |
DFI_11185 | obg | GCA_000419625_01688 | GCA_000419625_00783 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.586 |
DFI_11185 | rplN | GCA_000419625_01688 | GCA_000419625_00697 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.589 |
DFI_11185 | rplU | GCA_000419625_01688 | GCA_000419625_00781 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.521 |
DFI_11185 | rsfS | GCA_000419625_01688 | GCA_000419625_00578 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.561 |
DFI_11185 | trmB | GCA_000419625_01688 | GCA_000419625_01692 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.580 |
DFI_11185 | truD | GCA_000419625_01688 | GCA_000419625_02662 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.522 |