STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROH_09340Unannotated protein. (199 aa)    
Predicted Functional Partners:
dnaE
Unannotated protein.
    
 0.931
GCA_000332315_04020
Unannotated protein.
    
 
 0.905
priA
Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
 
 
 0.898
rpsF
Unannotated protein; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.814
rnhA
Unannotated protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.807
PROH_04340
Unannotated protein.
    
 
 0.807
PROH_07160
Unannotated protein.
    
   0.787
rplU
Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
    0.767
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.710
rplJ
Unannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
    0.700
Your Current Organism:
Prochlorothrix hollandica
NCBI taxonomy Id: 317619
Other names: P. hollandica PCC 9006 = CALU 1027, Prochlorothrix hollandica CCMP34, Prochlorothrix hollandica CCMP682, Prochlorothrix hollandica LI-2 ACC15-2, Prochlorothrix hollandica PCC 9006, Prochlorothrix hollandica PCC 9006 = CALU 1027, Prochlorothrix hollandica PCT-31, Prochlorothrix hollandica SAG 10.89
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