node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sala_0539 | Sala_0540 | Sala_0539 | Sala_0540 | GCN5-related N-acetyltransferase. | Hypothetical protein. | 0.723 |
Sala_0539 | tdk | Sala_0539 | Sala_0538 | GCN5-related N-acetyltransferase. | Thymidine kinase. | 0.826 |
Sala_0539 | truB | Sala_0539 | Sala_0541 | GCN5-related N-acetyltransferase. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.727 |
Sala_0540 | Sala_0539 | Sala_0540 | Sala_0539 | Hypothetical protein. | GCN5-related N-acetyltransferase. | 0.723 |
Sala_0540 | tdk | Sala_0540 | Sala_0538 | Hypothetical protein. | Thymidine kinase. | 0.773 |
Sala_0540 | truB | Sala_0540 | Sala_0541 | Hypothetical protein. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.741 |
Sala_0763 | Sala_2473 | Sala_0763 | Sala_2473 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Pyrimidine nucleoside phosphorylase-like protein. | 0.962 |
Sala_0763 | surE | Sala_0763 | Sala_0721 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
Sala_0763 | tdk | Sala_0763 | Sala_0538 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase. | 0.942 |
Sala_2473 | Sala_0763 | Sala_2473 | Sala_0763 | Pyrimidine nucleoside phosphorylase-like protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.962 |
Sala_2473 | surE | Sala_2473 | Sala_0721 | Pyrimidine nucleoside phosphorylase-like protein. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.928 |
Sala_2473 | tdk | Sala_2473 | Sala_0538 | Pyrimidine nucleoside phosphorylase-like protein. | Thymidine kinase. | 0.930 |
dut | surE | Sala_3181 | Sala_0721 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.903 |
dut | tdk | Sala_3181 | Sala_0538 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Thymidine kinase. | 0.971 |
dut | thyA | Sala_3181 | Sala_1332 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.969 |
dut | tmk | Sala_3181 | Sala_1257 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.949 |
prfA | tdk | Sala_2714 | Sala_0538 | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Thymidine kinase. | 0.826 |
surE | Sala_0763 | Sala_0721 | Sala_0763 | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.907 |
surE | Sala_2473 | Sala_0721 | Sala_2473 | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | Pyrimidine nucleoside phosphorylase-like protein. | 0.928 |
surE | dut | Sala_0721 | Sala_3181 | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.903 |