STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sala_1610Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (885 aa)    
Predicted Functional Partners:
Sala_1548
Pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
    
 0.963
Sala_0526
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.957
Sala_2792
Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+)., Phosphate acetyltransferase.
  
 
 0.955
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.934
Sala_1547
Thiamine pyrophosphate enzyme-like TPP-binding.
    
 0.930
Sala_0341
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.929
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.928
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.928
pdhA
Pyruvate dehydrogenase (lipoamide); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.909
Sala_1320
Transketolase; Belongs to the transketolase family.
  
 
 0.865
Your Current Organism:
Sphingopyxis alaskensis
NCBI taxonomy Id: 317655
Other names: S. alaskensis RB2256, Sphingopyxis alaskensis RB2256, Sphingopyxis alaskensis str. RB2256, Sphingopyxis alaskensis strain RB2256
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