STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sala_1838Glyoxalase/bleomycin resistance protein/dioxygenase. (128 aa)    
Predicted Functional Partners:
Sala_1839
Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
  
 0.880
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.811
Sala_1834
Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.696
Sala_1835
Ala-tRNA(Pro) hydrolase.
       0.537
Sala_1836
Glyoxalase/bleomycin resistance protein/dioxygenase.
 
    
0.525
Sala_1840
GCN5-related N-acetyltransferase.
  
    0.523
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.515
Sala_3030
Succinate dehydrogenase subunit C.
  
  
 0.455
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.452
Sala_1221
methylmalonyl-CoA mutase; N-terminal domain.
     
 0.446
Your Current Organism:
Sphingopyxis alaskensis
NCBI taxonomy Id: 317655
Other names: S. alaskensis RB2256, Sphingopyxis alaskensis RB2256, Sphingopyxis alaskensis str. RB2256, Sphingopyxis alaskensis strain RB2256
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.