STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG28328.1Hypothetical protein. (239 aa)    
Predicted Functional Partners:
OJG28412.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.824
OJG24582.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.824
OJG28327.1
Hypothetical protein.
       0.817
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 0.797
OJG27301.1
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.792
mprF
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.787
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.786
cinA
Competence/damage-inducible protein CinA domain; Belongs to the CinA family.
    
  0.786
OJG27217.1
Hypothetical protein.
  
     0.734
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.708
Your Current Organism:
Enterococcus caccae
NCBI taxonomy Id: 317735
Other names: CCUG 51564, E. caccae, Enterococcus caccae Carvalho et al. 2006, strain 2215-02
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.