STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG27511.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase. (155 aa)    
Predicted Functional Partners:
OJG27508.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
folE
GTP cyclohydrolase 1.
  
 0.999
OJG27512.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.999
OJG27509.1
RdgB/HAM1 family non-canonical purine NTP pyrophosphatase.
  
  
 0.993
OJG25294.1
FolC protein; Belongs to the folylpolyglutamate synthase family.
  
 
 0.843
OJG26786.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.814
OJG27911.1
YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
  0.813
OJG28231.1
Phospho-2-dehydro-3-deoxyheptonate aldolase.
   
 0.736
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 
 0.674
OJG28648.1
Hypothetical protein.
    
  0.641
Your Current Organism:
Enterococcus caccae
NCBI taxonomy Id: 317735
Other names: CCUG 51564, E. caccae, Enterococcus caccae Carvalho et al. 2006, strain 2215-02
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