STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Experiments
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[Homology]
Score
AFY41994.1Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ava:Ava_1498 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: DNA binding response regulator RpaA. (247 aa)    
Predicted Functional Partners:
sasA
Histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
 
  0.974
AFY45191.1
TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: npu:Npun_R0561 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted.
 
 
    0.888
AFY44645.1
TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: ana:alr3599 two-component response regulator; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator; TIGRFAM: Diguanylate cyclase, predicted.
 
   
0.880
AFY42693.1
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3452 periplasmic ligand-binding sensor domain; InterProIPR013655:IPR013767:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold; Signal tran [...]
 
 
0.873
AFY43243.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR008207:IPR013767:IPR 003018:IPR013955:IPR003661:IPR003594:IPR000014:IPR001610; KEGG: ava:Ava_0238 multi-component transcriptional regulator; PFAM: [...]
 
 
0.855
AFY41434.1
Multi-sensor signal transduction histidine kinase; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR000644:IPR013767:IPR013655:IPR 013656:IPR003661:IPR003594:IPR001610; KEGG: ana:alr1229 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; Cystathionine beta-synthase, core; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor doma [...]
 
 
 0.834
AFY45204.1
TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR013656:IPR003661:IPR 003594; KEGG: ava:Ava_3226 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS.
 
 
 0.788
AFY43549.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: npu:Npun_F2686 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bind [...]
  
 
0.766
AFY44634.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ava:Ava_3159 periplasmic sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Periplasmic Sensor Signal Transduction Histidine Kinase.
 
   0.764
AFY45154.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_F1277 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Two-component sensor histidine kinase.
   0.763
Your Current Organism:
Nostoc sp. PCC7107
NCBI taxonomy Id: 317936
Other names: N. sp. PCC 7107, Nostoc sp. PCC 7107
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