STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
AFY42414.1Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: gvi:gll4097 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two-component response regulator. (227 aa)    
Predicted Functional Partners:
AFY44843.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018:IPR011712:IPR003594; KEGG: amr:AM1_6282 GAF domain-containing protein; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; GAF; ATPase-like, ATP-binding domain; SMART: GAF; ATPase-like, ATP-binding domain; SPTR: GAF domain protein.
 
 
 0.871
AFY44149.1
PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: ava:Ava_2027 periplasmic sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Periplasmic Sensor Signal Transduction Histidine Kinase.
 
 0.839
AFY42693.1
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3452 periplasmic ligand-binding sensor domain; InterProIPR013655:IPR013767:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold; Signal tran [...]
  
 
 0.828
AFY43243.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR008207:IPR013767:IPR 003018:IPR013955:IPR003661:IPR003594:IPR000014:IPR001610; KEGG: ava:Ava_0238 multi-component transcriptional regulator; PFAM: [...]
  
 
 0.765
AFY42670.1
PFAM: Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: ava:Ava_0483 LuxR family transcriptional regulator; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator.
  
     0.759
AFY44640.1
COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: npu:Npun_F5759 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein.
  
     0.713
AFY43549.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: npu:Npun_F2686 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bind [...]
  
 
 0.697
AFY44404.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: npu:Npun_R0896 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoac [...]
  
 
 0.650
AFY41185.1
Integral membrane sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: npu:Npun_F1600 integral membrane sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transductio [...]
  
 
 0.606
AFY41380.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR003661:IPR003594:IPR 001789; KEGG: npu:Npun_F5479 integral membrane sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; Cache; Signal transduction response regulator, receiver doma [...]
  
 
 0.606
Your Current Organism:
Nostoc sp. PCC7107
NCBI taxonomy Id: 317936
Other names: N. sp. PCC 7107, Nostoc sp. PCC 7107
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