STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AFY44681.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ana:alr3386 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator. (125 aa)    
Predicted Functional Partners:
AFY43243.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR008207:IPR013767:IPR 003018:IPR013955:IPR003661:IPR003594:IPR000014:IPR001610; KEGG: ava:Ava_0238 multi-component transcriptional regulator; PFAM: [...]
 
 
0.835
AFY44682.1
Putative phytochrome sensor protein; COGs: COG3284 Transcriptional activator of acetoin/glycerol metabolism; InterPro IPR003018; KEGG: ana:alr3385 hypothetical protein; PFAM: GAF; SPTR: Alr3385 protein.
 
     0.826
AFY42693.1
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3452 periplasmic ligand-binding sensor domain; InterProIPR013655:IPR013767:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR000014:IPR001610; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold; Signal tran [...]
 
 
 0.815
AFY43449.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR000014:IPR001789:IPR013655:IPR003018:IPR 003661:IPR003594:IPR001610; KEGG: npu:Npun_R2903 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-3; GAF; [...]
 
 
0.811
AFY43852.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR013656:IPR013655:IPR 003661:IPR003594:IPR000014:IPR001610; KEGG: npu:Npun_R3691 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain; GAF; PAS [...]
 
 
0.810
AFY41434.1
Multi-sensor signal transduction histidine kinase; PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR000644:IPR013767:IPR013655:IPR 013656:IPR003661:IPR003594:IPR001610; KEGG: ana:alr1229 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; Cystathionine beta-synthase, core; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor doma [...]
 
 
 0.783
AFY45154.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_F1277 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Two-component sensor histidine kinase.
 
   0.783
AFY44325.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: cyh:Cyan8802_2594 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
  
   0.781
AFY41206.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003594; KEGG: ana:all4096 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Two-component hybrid sensor and regulator.
 
   0.755
AFY44967.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR003018; KEGG: ana:alr3982 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: Two-component sensor histidine kinase.
  
 
   0.751
Your Current Organism:
Nostoc sp. PCC7107
NCBI taxonomy Id: 317936
Other names: N. sp. PCC 7107, Nostoc sp. PCC 7107
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