STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (290 aa)    
Predicted Functional Partners:
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 
 0.968
mtaD
5-methylthioadenosine/S-adenosylhomocysteinedeam inase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
 
 0.922
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.904
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.590
AFY45322.1
KEGG: npu:Npun_F1500 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.450
AFY45321.1
COGs: COG4270 membrane protein; KEGG: npu:Npun_R3477 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.445
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
  
 0.430
AFY45324.1
KEGG: chu:CHU_1096 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.429
AFY44613.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: npu:Npun_R0622 hypothetical protein; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Putative uncharacterized protein.
  
  
 0.418
Your Current Organism:
Nostoc sp. PCC7107
NCBI taxonomy Id: 317936
Other names: N. sp. PCC 7107, Nostoc sp. PCC 7107
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