Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Sden_0010DNA-3-methyladenine glycosylase I. (187 aa)    
Predicted Functional Partners:
glyS
Glycine--tRNA ligase.
       0.605
glyQ
Glycine--tRNA ligase.
       0.605
Sden_2531
DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada / DNA-3-methyladenine glycosylase II.
     
 0.549
pepQ
Xaa-Pro dipeptidase. Metallo peptidase. MEROPS family M24B; Splits dipeptides with a prolyl residue in the C-terminal position.
      
 0.522
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
     
 0.522
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.480
Sden_0616
Homoserine dehydrogenase / aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
    0.412
Sden_2740
Homoserine dehydrogenase / aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
    0.412
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
  
    0.407
Sden_2530
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
   
 0.402
Your Current Organism:
Shewanella denitrificans
NCBI taxonomy Id: 318161
Other names: S. denitrificans OS217, Shewanella denitrificans OS217, Shewanella denitrificans str. OS217, Shewanella denitrificans strain OS217
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