Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sden_0809GGDEF domain. (585 aa)    
Predicted Functional Partners:
Sden_3670
GGDEF domain.
 
   0.808
Sden_1047
Diguanylate cyclase/phosphodiesterase.
  
   0.802
Sden_0375
Diguanylate cyclase/phosphodiesterase.
  
   0.791
Sden_0429
Diguanylate cyclase/phosphodiesterase.
  
   0.785
Sden_1862
Diguanylate cyclase/phosphodiesterase.
  
    0.776
Sden_0914
EAL domain protein.
  
    0.771
Sden_1592
Diguanylate phosphodiesterase.
  
    0.769
Sden_3352
Diguanylate cyclase/phosphodiesterase.
  
    0.656
Sden_2342
ATP-binding region, ATPase-like protein.
 
 
 0.624
Sden_0378
Diguanylate cyclase/phosphodiesterase / histidine kinase.
 
    0.565
Your Current Organism:
Shewanella denitrificans
NCBI taxonomy Id: 318161
Other names: S. denitrificans OS217, Shewanella denitrificans OS217, Shewanella denitrificans str. OS217, Shewanella denitrificans strain OS217
Server load: low (14%) [HD]