Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
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Sden_2000Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (874 aa)    
Predicted Functional Partners:
Sden_3767
Alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.987
Sden_2406
Formate acetyltransferase.
 
 
 0.975
Sden_2410
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.956
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.938
Sden_1943
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.935
Sden_2578
Iron-containing alcohol dehydrogenase.
 
 
0.933
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.926
Sden_3382
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.920
Sden_2339
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
0.918
Sden_1245
Malate synthase A.
  
 
 0.905
Your Current Organism:
Shewanella denitrificans
NCBI taxonomy Id: 318161
Other names: S. denitrificans OS217, Shewanella denitrificans OS217, Shewanella denitrificans str. OS217, Shewanella denitrificans strain OS217
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